• Overall this study provides compelling evidence that overexp

  2022-04-14

  

  Overall, this study provides compelling evidence that overexpression of catalase coupled with an enriched diet of OM3 fatty acids are metabolically beneficial. This combination was shown to increase adipose tissue expression of the GPR120/FFAR4, which by interacting with the Nrf2 pathway, resulted i

• br Introduction Inflammatory bowel diseases IBDs including

  2022-04-14

  

  Introduction Inflammatory bowel diseases (IBDs) including Crohn's disease and ulcerative colitis (Baumgart and Sandborn, 2012; Beaugerie et al., 2006) are typically characterized by chronic, progressive, and relapsing inflammation of the intestine. Although the exact pathogenesis of IBD is unknow

• Some years ago it has been

  2022-04-14

  

  Some years ago, it has been described that CD45RA+ CD62L+ naïve CD4+ T BMS-509744 can be further differentiated into two distinct subpopulations by analysing their surface expression of CD31(Kimmig et al., 2002a; Kohler and Thiel, 2009; Kohler et al., 2005b). CD31+ thymicnaive CD4+ T cells are enri

• br Regulation of gonadotropins by GnRH GnRH is

  2022-04-14

  

  Regulation of gonadotropins by GnRH GnRH is released from the hypothalamus, and its release pattern is known to be pulsatile. That is, the pulse frequency and amplitude of GnRH release vary physiologically during reproductive cycles in females, and differentially stimulate the production and rele

• In this study we find that DH

  2022-04-14

  

  In this study, we find that DH-CBD induces analgesic effects on inflammatory but not acute pain and the tlr4 receptor level of spinal α1 GlyRs increased after CFA paw injection. These results suggest that GlyR α1 is only involved in chronic pain. A possible explanation is that once the expression o

• Percentage contribution to free glutamate intake was also ca

  2022-04-14

  

  Percentage contribution to free glutamate intake was also calculated at the food item level. A list of the top 30 foods for children and adults are presented separately in Table 2. The top 4 foods included in this list are watermelon, raw; tomato catsup; tomatoes, raw; and roll, white, soft. These a

• The developed method was used to quantify RBC

  2022-04-14

  

  The developed method was used to quantify RBC membrane transport of the anomers of three monofluorinated analogs of glucose in a modified medium designed to provide stable metabolic properties of the cells over the lifetime of the experiment. This allowed us to evaluate the specific interaction (spe

• Due to the requirement of high end

  2022-04-14

  

  Due to the requirement of high-end methods such as total internal reflection fluorescence (TIRF) microscopy to visualize lipid rafts, isolation procedures are employed to study the protein content of lipid rafts [29]. The different methods utilized to isolated lipid rafts and other low density micro

• The functionally crucial arginine within M

  2022-04-14

  

  The functionally crucial arginine within M2 is not encoded by the gluR2 gene, but rather arises within the pre-mRNA by editing of a codon for the neutral glutamine residue25, 26. RNA editing at the Q/R site is specific to GluR2 and is extremely efficient. In neonatal and adult rat brain, almost 100%

• br Spatial working memory is GluR A

  2022-04-14

  

  Spatial working memory is GluR-A-dependent The radial maze task also allowed us to study hippocampus-dependent spatial working memory. On spatial working memory tasks, the correct spatial response that the animal must make varies from trial to trial and is dependent on some conditional, trial-spe

• An important difference between glucokinase and the other he

  2022-04-14

  

  An important difference between glucokinase and the other hexokinases is that it has a much lower affinity for glucose, such that it is not saturated at physiological blood glucose concentrations (Wilson, 1995, Wilson, 1997, Wilson, 2003, Wilson, 2004, Cárdenas et al., 1998). In addition, glucokinas

• cAMP is a key secondary

  2022-04-14

  

  cAMP is a key secondary messenger which transduces extracellular signals at glucagon receptors to intracellular effector molecules. cAMP-protein kinase A (PKA) pathway increases the gene expression of enzymes including phosphoenolpyruvate carboxykinase (PEPCK) and glucose 6-phosphatase (G6Pase) whic

• Next we asked how a common

  2022-04-14

  

  Next, we asked how a common activation marker of fibroblasts, Acta2, defined gene expression signatures in alveolar airspaces by using Acta2-mKO1 reporter mice (Fig. 2A). In the lungs of Acta2-mKO1 mice, mKO1 was expressed in smooth muscle cells and mesenchymal cells in g 36 (Fig. 2B). By sorting mK

• In order to test the influence of

  2022-04-14

  

  In order to test the influence of the initial depolarization, experiments were performed, where the degree of chloride substitution was varied, either by adding n-Ringer to Serdemetan australia incubated in a sucrose Ringer or by suspending the cells directly in Ringers identical to the final compo

• Conclusion By generating high quality hypocotyl transcriptom

  2022-04-13

  

  Conclusion By generating high-quality hypocotyl transcriptomes of a jute hypocotyl-defect mutant and its wild-type comprising the largest number of annotated unigenes (39,076), we identified a complete array of structurally and functionally diverse β-galactosidases. Our proposed domain-centric clas

14058 records 415/938 page Previous Next First page 上5页 411412413414415 下5页 Last page